Understanding Lung Cancer —
Your Complete Guide.
A comprehensive overview of lung cancer — what it is, its types, causes, and treatment options — explained clearly by Dr. Aditya Sarin, so you can approach diagnosis and care with confidence.
This page is for informational purposes only and does not constitute medical advice, diagnosis or treatment. Every case of lung cancer is different. Please consult Dr. Aditya Sarin or a qualified oncologist for evaluation, diagnosis and a treatment plan specific to your condition.
Non-Small Cell
Lung Cancer
Early Detection
Recognising symptoms early and seeking timely screening improves outcomes significantly.
Accurate Diagnosis
Scans, biopsies, and molecular testing confirm the cancer type and stage precisely.
Personalised Treatment
Surgery, chemotherapy, targeted therapy, or immunotherapy — tailored to your case.
Ongoing Support
Follow-up care, rehabilitation, and emotional support throughout your recovery journey.
What is Lung Cancer?
Lung cancer is a type of cancer that starts in the lungs when abnormal cells grow uncontrollably. It is one of the most common and serious types of cancer worldwide, often associated with smoking but also occurring in non-smokers due to genetic, environmental, and other factors.
Lung cancer may not cause noticeable symptoms in its early stages, making regular screening crucial — especially for those at higher risk. Early detection dramatically improves the likelihood of successful treatment.
Starts in the Lungs
Abnormal cells in lung tissue divide uncontrollably, forming a tumour that can grow and spread.
Can Spread to Other Organs
Without treatment, lung cancer can metastasize to the brain, bones, liver, and adrenal glands.
Highly Treatable if Caught Early
Stage I and II lung cancers have significantly better outcomes with surgical and targeted treatments.
Multiple Treatment Options
Modern oncology offers surgery, chemotherapy, targeted therapy, immunotherapy, and radiation — often in combination.
Types of Lung Cancer
Lung cancer is primarily classified into two major categories based on how the cancer cells look under a microscope. Each type behaves differently and requires a distinct treatment approach.
Adenocarcinoma
The most common subtype, often found in non-smokers. Usually starts in the outer regions of the lungs and is associated with specific gene mutations targetable with precision therapy.
Squamous Cell Carcinoma
Strongly linked to smoking, this type is found in the central airways of the lungs and is often detected when it causes breathing obstruction or bleeding.
Large Cell Carcinoma
A rare and aggressive form of non-small cell lung cancer that can appear anywhere in the lungs and tends to grow and spread quickly.
Small Cell Lung Cancer
A fast-growing cancer almost exclusively found in heavy smokers. It spreads rapidly to other organs and is typically treated with chemotherapy and radiation rather than surgery.
Symptoms of Lung Cancer
Lung cancer may not cause noticeable symptoms in its early stages. As the disease progresses, the following signs may appear. Persistent or unexplained symptoms should prompt immediate medical evaluation.
Early detection saves lives. If you experience a persistent cough, chest pain, or breathing difficulties, do not delay — book an appointment with Dr. Aditya Sarin today for a thorough evaluation.
Causes & Risk Factors
Several factors can increase the risk of developing lung cancer. While smoking remains the leading cause, lung cancer also affects non-smokers due to environmental and genetic factors.
Diagnosis of Lung Cancer
Early and accurate diagnosis is critical to achieving the best treatment outcomes. Dr. Aditya Sarin uses the latest diagnostic tools to confirm the presence, type, and stage of lung cancer with precision.
Chest X-ray
The initial screening tool used to detect visible lung abnormalities, masses, or shadows that warrant further investigation.
CT Scan
Provides detailed cross-sectional imaging of the lungs to identify the size, location, and extent of any tumours and lymph node involvement.
Biopsy
A tissue sample is collected via bronchoscopy, CT-guided needle biopsy, or surgery to definitively confirm cancer and determine its exact type.
PET Scan
Detects metabolically active cancer cells throughout the body, revealing whether cancer has spread to other organs or lymph nodes.
Molecular & Genetic Testing
Identifies specific gene mutations (EGFR, ALK, ROS1, KRAS) that guide the selection of targeted therapies for personalised treatment.
Stages of Lung Cancer
Staging describes how far the cancer has spread and directly shapes the treatment approach. Non-small cell lung cancer, which accounts for 85 percent of cases, is staged using the AJCC TNM system into Stages I through IV. Small cell lung cancer, the remaining 15 percent, uses a simpler limited or extensive staging system instead, reflecting how differently the two types behave. This staging guidance is current as of 2026.
Source: American Cancer Society, Non-small Cell Lung Cancer Stages.
Survival Rates by Stage
Survival statistics are population averages. They describe outcomes across large groups of patients and do not predict what will happen to any individual patient.
Lung cancer survival rate in the US — Non-small cell lung cancer
Source: American Cancer Society, Lung Cancer Survival Rates, based on SEER data for cases diagnosed between 2015 and 2021.
Lung cancer survival rate in the US — Small cell lung cancer
Source: American Cancer Society, Lung Cancer Survival Rates, based on SEER data for cases diagnosed between 2012 and 2018.
Lung cancer survival rate in India
Nationally representative, stage-wise survival data specific to lung cancer is limited in India. Published research citing National Cancer Registry Programme data notes that developing countries, including India, report a mean 5-year survival of around 15 percent — roughly three times lower than developed countries — largely because 75 percent of cases in India are diagnosed at Stage III or IV.
Treatment Options for Lung Cancer
The treatment approach is tailored to the cancer type, stage, and the patient's overall health. Dr. Aditya Sarin offers a comprehensive, multidisciplinary approach covering all established and emerging treatment modalities.
Surgery
Lobectomy, pneumonectomy, or segmentectomy — the appropriate procedure depends on tumour size, location, and stage. Offers the best chance of cure in early-stage disease.
Radiation Therapy
High-energy beams target and destroy cancer cells while minimising damage to surrounding healthy tissue. Often combined with chemotherapy.
Chemotherapy
Drug treatment used to kill cancer cells, often given before surgery (neoadjuvant), after surgery (adjuvant), or as the primary treatment in advanced cases.
Targeted Therapy
Precision medicines that target specific genetic mutations (EGFR, ALK, ROS1) in cancer cells to block their growth with fewer side effects than chemotherapy.
Immunotherapy
Checkpoint inhibitors such as PD-1/PD-L1 blockers help the immune system recognise and fight lung cancer cells more effectively, especially in advanced NSCLC.
Palliative Care
For advanced cancer, palliative care focuses on relieving symptoms, improving quality of life, and providing holistic support to patients and their families.
Latest Advances in Lung Cancer Treatment
Lung cancer treatment has advanced significantly over the past year, particularly in precision therapies matched to specific genetic mutations. As of 2026, notable developments include the following.
A strong year for precision oncology in NSCLC
The FDA approved seven new biomarker-driven therapies for non-small cell lung cancer in 2025 alone, covering mutations including EGFR, HER2, MET, and ROS1.
Among them, datopotamab deruxtecan received accelerated approval in June 2025 for EGFR-mutated NSCLC that has progressed after standard treatment.
Expanded option for HER2-mutant NSCLC
On February 26, 2026, the FDA approved zongertinib for adults with advanced NSCLC whose tumours carry HER2 tyrosine kinase domain activating mutations — expanding on its original accelerated approval from August 2025.
Source: Boehringer Ingelheim — FDA Approves Targeted Therapy for HER2-Mutant Advanced NSCLC, 2026.
First adjuvant targeted therapy for ALK-positive NSCLC
Based on the ALINA trial, adjuvant alectinib was approved for resected, early-stage ALK-positive NSCLC — reducing the risk of recurrence or death by 76 percent compared with chemotherapy.
This is the first molecularly targeted adjuvant therapy specifically for this subtype.
Life After Lung Cancer Treatment
Completing treatment is a significant milestone. Recovery focuses on rebuilding lung function, physical strength, and emotional wellbeing — with comprehensive support at every step.
Regular Follow-ups
Scheduled scans and check-ups to monitor for recurrence, manage long-term side effects, and assess overall health.
Lifestyle Changes
Guidance on quitting smoking, maintaining a healthy diet, and staying physically active to support long-term recovery and reduce recurrence risk.
Pulmonary Rehabilitation
Structured breathing exercises, physiotherapy, and pulmonary programmes to restore lung function and improve exercise capacity.
Emotional & Psychological Support
Counselling, peer support groups, and mental health resources for patients and their families throughout and after treatment.
Facing Lung Cancer with Confidence
"Early detection, precise diagnosis, and a personalised treatment plan are the cornerstones of the best possible outcome in lung cancer care."
— Dr. Aditya Sarin, Medical OncologistFrequently Asked Questions about Lung Cancer
Can non-smokers get lung cancer?
What is the difference between non-small cell and small cell lung cancer?
Is lung cancer screening recommended for everyone?
What does molecular or genetic testing add to lung cancer treatment?
Can lung cancer spread without causing symptoms?
Is immunotherapy an option for all lung cancer patients?
What is the best treatment approach for Lung Cancer in Delhi?
Why Trust Dr. Aditya Sarin for Lung Cancer Care?
ESMO Board Certified · Harvard Trained · Sir Ganga Ram Hospital, New Delhi
Expert Oncology Care
ESMO Board Certified oncologist with advanced training in precision oncology and cancer genomics from Harvard Medical School, specialising in lung cancer diagnosis and treatment.
Advanced Technology
Cutting-edge diagnostic tools including PET-CT, EBUS bronchoscopy, and next-generation molecular sequencing for accurate staging and treatment selection.
Multidisciplinary Care
Integrated team approach combining surgery, chemotherapy, targeted therapy, radiation, and palliative care for holistic patient management.
Post-Treatment Support
Comprehensive rehabilitation, lifestyle guidance, pulmonary therapy, and mental health support to help you thrive after treatment.
Book Your Lung Cancer Consultation
Speak with Dr. Aditya Sarin to discuss your symptoms, understand your diagnosis, and take the first step toward the best possible outcome.
📅 Book Your Consultation